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KMID : 0363219740120020021
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Korean Journal of Dermatology
1974 Volume.12 No. 2 p.21 ~ p.24
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Clinical Effects of Combined Treatment of Prednisolone and Psoralen on Vitiligo
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朴洋子/Park, Yang Ja
李順福/卞東吉/Lee, Soon Bok/Byun, Dong Gil
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Abstract
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Although the psoralen therapy has been used extensively on vitligo since the introduction by El-Mofty on 1948, the result has not been satisfactory. Recent investigations showed that the autoimmune mechanism might be the: causative factor to the development of vitiligo, and the use of steroid might be expected to be beneficial in the treatment of this disorder.
Authors tried the combined treatment of prednisolone and psoralen on vitiligo and the results obtained are as follows;
1. Repigmentations began to develop from injected area of prednisolone as well as from hair follicles and peripheral area of the lesions.
2. More satisfactory responses were obtained on the widespread and symmetrical lesions of shorter duration than on the lesions of localized and long duration.
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